Colombo, Sri Lanka: Dengue virus is transmitted from person to person by Aedes mosquito. Children less than 15 years are the most common victims. The youngest was a neonate, and the oldest was 12 years of age. However, the principles of fluid therapy can be summarized as follows: As mentioned previously, the number of trials assessing the efficacy of steroids is small and has yielded conflicting results.
The role of different inotropic and vasopressor agents in dengue shock has not been investigated in clinical trials. Despite these, research is still ongoing because the cost-effectiveness of an efficacious vaccine will be massive in all endemic areas.
Blood products In practice, platelet transfusions are usually given to patients who develop serious hemorrhagic manifestations or have very low platelet counts, although the exact platelet count at which platelets should be given has not been defined.
Administration of fluids should be guided by frequent monitoring and assessment of intravascular volume status during the critical stage, and fluids should never be administered at a constant rate without monitoring.
Acute management of dengue shock syndrome: The case definition, diagnosis, and management for dengue fever were as per the revised World Health Organization WHO guidelines However, the study was considered to be underpowered.
Associations of antibody responses, viremia levels as determined by real-time polymerase chain reaction [PCR]and serotypes as determined by multiplex PCR with disease severity were evaluated Results.
Postgrad Med J. Nimmannitya S. There is no specific treatment for the infection, and management is only supportive care with judicious fluid management during the critical phase coupled with continuous monitoring.
If the patient is still ill and in critical phase with low platelet counts, always suspect bleeding. J Med Assoc Thai. There is currently insufficient evidence to make any recommendation regarding the use of intravenous immunoglobulins in dengue shock, 6 and further studies are required.
Between 50 million and million DENV infections occur yearly [ 2 ].
Presents as acute biphasic fever with myalgia, arthralgia Break bone feverheadache, rash, leukopenia and occasionally with unusual hemorrhage.
All the data from hospital case records were entered in a structured clinical proforma, and the data were retrospectively analyzed.
The ideal dose or rapidity with which fluid should be infused has not been demonstrated in the trials, and recommendations are based on treatment practices in centers which have had significant experience in treating dengue patients.
There is a lack of uniformity in assay methods employed in earlier vaccine trials, making it difficult to undertake a head-to-head comparison.CASE REPORT Acta Medica Indonesiana - The Indonesian Journal of Internal Medicine 57 Acute Pancreatitis in Dengue Hemorrhagic Fever Marcellus Simadibrata.
Dengue hemorrhagic fever: Children less than 15 years are the most common victims. It presents with acute onset of fever with nonspecific constitutional symptoms and signs of hemorrhagic diathesis, which may progress to fatal shock (Dengue shock syndrome, DSS).Author: Dr Vishal Dublish, Dr Ira Shah.
· Most patients with dengue experience mild disease, dengue fever (DF), while few develop the life-threatening diseases dengue hemorrhagic fever (DHF) or dengue shock syndrome (DSS). No laboratory tests predict DHF or DSS.
We evaluated whether the serum chymase level can predict DHF or DSS in adult and pediatric patients and the influence of preexisting conditions (PECs) on chymase Cited by: 3. Dengue infection is caused by any of four dengue virus serotypes. The clinical manifestations range from asymptomatic infection to undifferentiated fever, dengue fever and dengue hemorrhagic fever (DHF).Cited by: A, Revised dengue fever case 1classification,adapted from World Health Organization B, Clinical course and labo- B, Clinical course and labo- ratory diagnosis of dengue fever.
dengue illness making an incidence of %. 96 (49%) had dengue fever, 80(%) had dengue haemorrhagic fever and 20(%) had dengue shock syndrome. years was the most common age group affected with M:F ratio of In this study most of our patients 89% presented in the post monsoon periods (August- November).